Research ArticleORIGINAL RESEARCH
Photon-counting detector CT of the brain reduces variability of Hounsfield units and has a mean offset compared with energy-integrating detector CT
Thomas Stein, Friederike Lang, Stephan Rau, Marco Reisert, Maximilian. F. Russe, Till Schürmann, Anna Fink, Elias Kellner, Jakob Weiss, Fabian Bamberg, Horst Urbach and Alexander Rau
American Journal of Neuroradiology July 2025, ajnr.A8910; DOI: https://doi.org/10.3174/ajnr.A8910
Thomas Stein
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Friederike Lang
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Stephan Rau
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Marco Reisert
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Maximilian. F. Russe
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Till Schürmann
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Anna Fink
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Elias Kellner
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Jakob Weiss
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Fabian Bamberg
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Horst Urbach
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).
Alexander Rau
From the Department of Diagnostic and Interventional Radiology, Universityhospital Freiburg, Germany (TS, FL, SR, MFR, TS, AF, JW, FB), Medical Physics, Universityhospital Freiburg, Germany (MR, EK), Department of Stereotactic and Functional Neurosurgery, Universityhospital Freiburg, Germany (MR), and the Department of Neuroradiology, Universityhospital Freiburg, Germany (HU, AR).

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Accepted Manuscript
Thomas Stein, Friederike Lang, Stephan Rau, Marco Reisert, Maximilian. F. Russe, Till Schürmann, Anna Fink, Elias Kellner, Jakob Weiss, Fabian Bamberg, Horst Urbach, Alexander Rau
Photon-counting detector CT of the brain reduces variability of Hounsfield units and has a mean offset compared with energy-integrating detector CT
American Journal of Neuroradiology Jul 2025, ajnr.A8910; DOI: 10.3174/ajnr.A8910
Accepted Manuscript
Photon-counting detector CT of the brain reduces variability of Hounsfield units and has a mean offset compared with energy-integrating detector CT
Thomas Stein, Friederike Lang, Stephan Rau, Marco Reisert, Maximilian. F. Russe, Till Schürmann, Anna Fink, Elias Kellner, Jakob Weiss, Fabian Bamberg, Horst Urbach, Alexander Rau
American Journal of Neuroradiology Jul 2025, ajnr.A8910; DOI: 10.3174/ajnr.A8910
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