CT Findings and Clinical Features as Markers for Patient Outcome in Primary Pontine Hemorrhage

American Journal of Neuroradiology

TABLE 1:

CT parameters in 29 patients with PPH stratified by outcome

CT Parameter	Severe Disability, GOS Score < 4 (n = 17)	Mild Disability Good Recovery, GOS Score ≥ 4 (n = 12)	P Value^*	Death (n = 9)	Survivors (n = 20)	P Value^*
Mean hematoma volume (mL)	6.6 ± 2.7	2.8 ± 1.6		7.9 ± 2.6	3.7 ± 2.1
Hematoma ≥ 4 mL	14 (82)	3 (25)	.006	9 (100)	8 (40)	.003
Hematoma < 4 mL	3 (17)	9 (75)	.006	0	12 (60)	.003
Hematoma location
Dorsal	0	9 (75)	<.001	0	9 (45)	.011
Ventral	12 (70)	3 (25)	<.001	4 (44)	9 (45)	.23
Massive	5 (29)	0	.002	5 (55)	0	<.001
Intraventricular hematoma extension	6 (35)	1 (8)	.18	5 (55)	2 (10)	.01
Hydrocephalus	7 (41)	2 (16)	.23	6 (66)	3 (15)	.01

TABLE 2:

Clinical parameters in 29 patients with PPH stratified by outcome

Clinical Parameter	Severe Disability, GOS Score < 4 (n = 17)	Mild Disability, Good Recovery, GOS Score ≥ 4 (n = 12)	P Value^*	Death (n = 9)	Survivors (n = 20)	P Value^*
Coma on admission	11 (64)	1 (8)	0.03	7 (77)	2 (10)	.014
Abnormal pupils	10 (58)	4 (33)	.26	6 (66)	8 (40)	.24
Scores (mean ± SD)
GCS on admission	4.3 ± 2.3	10.3 ± 3.0	.001	3.1 ± 0.3	8.5 ± 3.6	.03
GCS on discharge	6.7 ± 4.3	12.2 ± 1.5	<.001	—	11.7 ± 1.8	<.001
NIHSS on admission	36.4 ± 7.3	18.7 ± 11.0	.008	39 ± 2.4	24.6 ± 12.7	.40
NIHSS on discharge	30.4 ± 13.6	8.6 ± 4.6	<.001	—	12.1 ± 7.3	<.001
Age (mean, 59 ± 13 y)
≥65 years (n = 11)	8 (47)	3 (25)	.20	7 (77)	4 (20)	.01
<65 years (n = 18)	9 (52)	9 (75)	.20	2 (22)	16 (80)	.01
History of hypertension	15 (88)	9 (75)	.62	9 (100)	15 (75)	.15
Mechanical ventilation	16 (94)	2 (16)	<.001	9 (100)	9 (45)	.005