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    Fig 1.

    A 46-year-old woman with a history of idiopathic hypereosinophilic syndrome presented with multiple cranial nerve palsies.

    A, Axial T2-weighted MR image shows a hypointense left skull base mass (arrows) at the region of the left basisphenoid.

    B, Enhanced fat-suppressed axial T1-weighted MR image demonstrates the enhancing left skull base mass with involvement of the clivus (C), foramen rotundum (thin arrows), dura (thick arrows), and pterygopalatine fossa (P).

    C, Enhanced fat-suppressed axial T1-weighted MR image shows a solidly enhancing mass (similar in appearance to a meningioma) involving the left cavernous sinus with some narrowing of the adjacent internal carotid artery (thin arrow), with associated thick dural enhancement (thick arrows). Also note involvement of the left orbital apex (O).

  • Fig 2.
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    Fig 2.

    A, At medium power, most tissue fragments showed attenuated fibrosis (thick arrows) around nerves (thin arrows) and vessels (arrowhead), along with crushed inflammatory cells. Focal areas of fat necrosis are present at the periphery of the fibroinflammatory mass. (hematoxylin-eosin [H&E], original magnification ×100)

    B. At high power, lymphocytes, histiocytes, plasma cells (arrow), and scattered eosinophils (arrowhead) are seen within the fatty tissue. (H&E, original magnification ×400)

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American Journal of Neuroradiology: 28 (5)
American Journal of Neuroradiology
Vol. 28, Issue 5
May 2007
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Cite this article
M.L. Battineni, S.L. Galetta, J. Oh, M. Lango, J.J. Brooks, S.J. Schuster, L.A. Loevner
Idiopathic Hypereosinophilic Syndrome with Skull Base Involvement
American Journal of Neuroradiology May 2007, 28 (5) 971-973;

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Idiopathic Hypereosinophilic Syndrome with Skull Base Involvement
M.L. Battineni, S.L. Galetta, J. Oh, M. Lango, J.J. Brooks, S.J. Schuster, L.A. Loevner
American Journal of Neuroradiology May 2007, 28 (5) 971-973;
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