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References

  1. ↵
    Paty DW, Li DK. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study Group. Neurology 1993;43:662–67
    Abstract/FREE Full Text
  2. Rovaris M, Comi G, Rocca MA, et al. Short-term brain volume change in relapsing-remitting multiple sclerosis: effect of glatiramer acetate and implications. Brain 2001;124:1803–12
    Abstract/FREE Full Text
  3. Weiner HL, Guttmann CR, Khoury SJ, et al. Serial magnetic resonance imaging in multiple sclerosis: correlation with attacks, disability, and disease stage. J Neuroimmunol 2000;104:164–73
    CrossRefPubMedWeb of Science
  4. Cotton F, Weiner HL, Jolesz FA, et al. MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals. Neurology 2003;60:640–46
    Abstract/FREE Full Text
  5. ↵
    Guttmann CR, Meier DS, Holland CM. Can MRI reveal phenotypes of multiple sclerosis? Magn Reson Imaging 2006;24:475–81
    CrossRefPubMed
  6. ↵
    The IFNB Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group. Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial. Neurology 1995;45:1277–85
    Abstract/FREE Full Text
  7. ↵
    Tan IL, van Schijndel RA, Fazekas F, et al. Image registration and subtraction to detect active T(2) lesions in MS: an interobserver study. J Neurol 2002;249:767–73
    CrossRefPubMedWeb of Science
  8. ↵
    Warfield S, Dengler J, Zaers J, et al. Automatic identification of gray matter structures from MRI to improve the segmentation of white matter lesions. J Image Guid Surg 1995;1:326–38
    CrossRefPubMed
  9. ↵
    Guttmann CR, Kikinis R, Anderson MC, et al. Quantitative follow-up of patients with multiple sclerosis using MRI: reproducibility. J Magn Reson Imaging 1999;9:509–18
    CrossRefPubMedWeb of Science
  10. ↵
    Warfield SK, Kaus M, Jolesz FA, et al. Adaptive, template moderated, spatially varying statistical classification. Med Image Anal 2000;4:43–55
    CrossRefPubMedWeb of Science
  11. Molyneux PD, Tofts PS, Fletcher A, et al. Precision and reliability for measurement of change in MRI lesion volume in multiple sclerosis: a comparison of two computer assisted techniques. J Neurol Neurosurg Psychiatry 1998;65:42–47
    Abstract/FREE Full Text
  12. Dastidar P, Heinonen T, Vahvelainen T, et al. Computerised volumetric analysis of lesions in multiple sclerosis using new semi-automatic segmentation software. Med Biol Eng Comput 1999;37:104–07
    CrossRefPubMed
  13. Alfano B, Brunetti A, Larobina M, et al. Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis. J Magn Reson Imaging 2000;12:799–807
    CrossRefPubMedWeb of Science
  14. Ashton EA, Takahashi C, Berg MJ, et al. Accuracy and reproducibility of manual and semiautomated quantification of MS lesions by MRI. J Magn Reson Imaging 2003;17:300–08
    CrossRefPubMedWeb of Science
  15. Anbeek P, Vincken KL, van Osch MJ, et al. Automatic segmentation of different-sized white matter lesions by voxel probability estimation. Med Image Anal 2004;8:205–15
    CrossRefPubMed
  16. Anbeek P, Vincken KL, van Osch MJ, et al. Probabilistic segmentation of white matter lesions in MR imaging. Neuroimage 2004;21:1037–44
    CrossRefPubMed
  17. ↵
    Duan Y, Moscufo N, Pouwels PJ, et al. Synergies of high-resolution multi-channel lesion segmentation in multiple sclerosis: MPRAGE, 3D FLAIR, 3D T2WI and 3D DIR. In: ISMRM. May2006 , Seattle; ISMRM:2006:3116
  18. ↵
    Tan IL, van Schijndel RA, Pouwels PJ, et al. Serial isotropic three-dimensional fast FLAIR imaging: using image registration and subtraction to reveal active multiple sclerosis lesions. AJR Am J Roentgenol 2002;179:777–82
    PubMedWeb of Science
  19. ↵
    Wei X, Warfield SK, Zou KH, et al. Quantitative analysis of MRI signal abnormalities of brain white matter with high reproducibility and accuracy. J Magn Reson Imaging 2002;15:203–09
    CrossRefPubMedWeb of Science
  20. ↵
    Hohol MJ, Guttmann CR, Orav J, et al. Serial neuropsychological assessment and magnetic resonance imaging analysis in multiple sclerosis. Arch Neurol 1997;54:1018–25
    CrossRefPubMedWeb of Science
  21. ↵
    Friston KJ, Ashburner J, Frith C, et al. Spatial registration and normalization of images. Hum Brain Mapp 1995;2:165–89
  22. ↵
    Kiebel SJ, Ashburner J, Poline JB, et al. MRI and PET coregistration–a cross validation of statistical parametric mapping and automated image registration. Neuroimage 1997;5:271–79
    CrossRefPubMed
  23. ↵
    Meier DS, Guttmann CR. Time-series analysis of MRI intensity patterns in multiple sclerosis. Neuroimage 2003;20:1193–209
    CrossRefPubMed
  24. ↵
    Altman DG, Bland JM. Comparison of methods of measuring blood pressure. J Epidemiol Community Health 1986;40:274–77
    FREE Full Text
  25. ↵
    Lee MA, Smith S, Palace J, et al. Defining multiple sclerosis disease activity using MRI T2-weighted difference imaging. Brain 1998;121:2095–102
    Abstract/FREE Full Text
  26. ↵
    Miller DH, Barkhof F, Nauta JJ. Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis. Brain 1993;116:1077–94
    Abstract/FREE Full Text
  27. ↵
    Fisher E, Rudick RA, Simon JH, et al. Eight-year follow-up study of brain atrophy in patients with MS. Neurology 2002;59:1412–20
    Abstract/FREE Full Text
  28. ↵
    Guttmann C, Warfield S, Guimond A, et al. Variability of brain atrophy estimates in multiple sclerosis. Proc Intl Soc Mag Reson Med 2000;1188
  29. ↵
    Molyneux PD, Miller DH, Filippi M, et al. The use of magnetic resonance imaging in multiple sclerosis treatment trials: power calculations for annual lesion load measurement. J Neurol 2000;247:34–40
    CrossRefPubMedWeb of Science
  30. ↵
    PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. Lancet 1998;352:1498–504
    CrossRefPubMedWeb of Science
  31. ↵
    Gawne-Cain ML, Webb S, Tofts P, et al. Lesion volume measurement in multiple sclerosis: how important is accurate repositioning? J Magn Reson Imaging 1996;6:705–13
    PubMedWeb of Science
  32. ↵
    Rovaris M, Gawne-Cain ML, Sormani MP, et al. The effect of repositioning on brain MRI lesion load assessment in multiple sclerosis: reliability of subjective quality criteria. J Neurol 1998;245:273–75
    CrossRefPubMed
  33. ↵
    Meier DS, Weiner HL, Guttmann CR. Time-series modeling of MS disease activity: a promising window on disease progression and repair potential. Neurotherapeutics 2007;4:485–98
    CrossRefPubMed
  34. ↵
    Rudick RA, Fisher E, Lee JC, et al. Brain atrophy in relapsing multiple sclerosis: relationship to relapses, EDSS, and treatment with interferon beta-1a. Mult Scler 2000;6:365–72
    Abstract/FREE Full Text
  35. ↵
    Kutzelnigg A, Lucchinetti CF, Stadelmann C, et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005;128:2705–12
    Abstract/FREE Full Text
  36. ↵
    Wattjes MP, Lutterbey GG, Gieseke J, et al. Double inversion recovery brain imaging at 3T: diagnostic value in the detection of multiple sclerosis lesions. AJNR Am J Neuroradiol 2007;28:54–59
    Abstract/FREE Full Text
  37. Mugler JP 3rd, Bao S, Mulkern RV, et al. Optimized single-slab three-dimensional spin-echo MR imaging of the brain. Radiology 2000;216:891–99
    CrossRefPubMedWeb of Science
  38. Pouwels PJ, Kuijer JP, Mugler JP 3rd, et al. Human gray matter: feasibility of single-slab 3D double inversion-recovery high-spatial-resolution MR imaging. Radiology 2006;241:873–79
    CrossRefPubMedWeb of Science
  39. ↵
    Geurts JJ, Pouwels PJ, Uitdehaag BM, et al. Intracortical lesions in multiple sclerosis: improved detection with 3D double inversion-recovery MR imaging. Radiology 2005;236:254–60
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 29 (2)
American Journal of Neuroradiology
Vol. 29, Issue 2
February 2008
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Cite this article
Y. Duan, P.G. Hildenbrand, M.P. Sampat, D.F. Tate, I. Csapo, B. Moraal, R. Bakshi, F. Barkhof, D.S. Meier, C.R.G. Guttmann
Segmentation of Subtraction Images for the Measurement of Lesion Change in Multiple Sclerosis
American Journal of Neuroradiology Feb 2008, 29 (2) 340-346; DOI: 10.3174/ajnr.A0795

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Segmentation of Subtraction Images for the Measurement of Lesion Change in Multiple Sclerosis
Y. Duan, P.G. Hildenbrand, M.P. Sampat, D.F. Tate, I. Csapo, B. Moraal, R. Bakshi, F. Barkhof, D.S. Meier, C.R.G. Guttmann
American Journal of Neuroradiology Feb 2008, 29 (2) 340-346; DOI: 10.3174/ajnr.A0795
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