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Research ArticleBrainC

Suspicious Neuroimaging Pattern of Thrombotic Microangiopathy

T.N. Ellchuk, L.M. Shah, R.H. Hewlett and A.G. Osborn
American Journal of Neuroradiology April 2011, 32 (4) 734-738; DOI: https://doi.org/10.3174/ajnr.A2351
T.N. Ellchuk
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L.M. Shah
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R.H. Hewlett
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A.G. Osborn
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    Fig 1.

    Case 6. A, Axial noncontrast CT scan demonstrates nonspecific peripheral hypoattenuation (arrow). B, Axial T2 MR image demonstrates cortical and subcortical hyperintensity (arrow) without appreciable hemorrhage. C, B = 1000 DWI MR image reveals multifocal cortical and subcortical hyperintensities (arrows). D, The corresponding apparent diffusion coefficient map demonstrates hypointensities in a similar distribution (arrows), consistent with infarction. E and F, GRE MR image reveals subtle blooming from petechial hemorrhage (E, arrow), better demonstrated on the SWI MR image (F, arrow).

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    Fig 2.

    Case 12. A, B = 1000 DWI MR image reveals multifocal cortical and subcortical hyperintensities (arrows). B, The corresponding apparent diffusion coefficient map demonstrates hypointensities in a similar distribution (arrows), consistent with infarction. C, GRE MR image reveals petechial hemorrhage (arrow) in a similar distribution.

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    Fig 3.

    Cases 4 and 8. Axial noncontrast CT scans demonstrate peripheral hemorrhagic infarctions (arrows) in 2 patients with DIC.

Tables

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  • Patient demographics and clinical information

    No.SexAge (yr)DiagnosisImagingUnderlying Disease
    1M47DICCTMetastatic colon cancer
    MRISplenic infarct
    2F70DICCTStaphylococcus aureus bacterial endocarditis
    CTVaRenal, splenic infarcts
    MRI
    3M22DICCTStaphylococcus aureus bacterial endocarditis
    CTVaMeningitis
    MRI
    4M64DICCTGroup B streptococcal sepsis
    MRI
    MRVa
    5M60DICCTStreptococcus pneumoniae bacterial endocarditis
    MRICLL in remission
    6F44TTPCTAML
    MRIBreast cancer
    7M67DICCTMitral valve vegetation
    MRI
    MRVa
    8M7DICCTNone
    9M24mHTNCTRenal transplant
    MRI
    10M18mHTNCTCocaine use
    11F66mHTNMRIRenal failure
    12M7DICCTDown syndrome
    MRI
    • a Venography findings were negative.

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American Journal of Neuroradiology: 32 (4)
American Journal of Neuroradiology
Vol. 32, Issue 4
1 Apr 2011
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Cite this article
T.N. Ellchuk, L.M. Shah, R.H. Hewlett, A.G. Osborn
Suspicious Neuroimaging Pattern of Thrombotic Microangiopathy
American Journal of Neuroradiology Apr 2011, 32 (4) 734-738; DOI: 10.3174/ajnr.A2351

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Suspicious Neuroimaging Pattern of Thrombotic Microangiopathy
T.N. Ellchuk, L.M. Shah, R.H. Hewlett, A.G. Osborn
American Journal of Neuroradiology Apr 2011, 32 (4) 734-738; DOI: 10.3174/ajnr.A2351
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

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