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Research ArticleBrain
Open Access

A Distinct MR Imaging Phenotype in Amyotrophic Lateral Sclerosis: Correlation between T1 Magnetization Transfer Contrast Hyperintensity along the Corticospinal Tract and Diffusion Tensor Imaging Analysis

G. Carrara, C. Carapelli, F. Venturi, M.M. Ferraris, L. Lequio, A. Chiò, A. Calvo, S. Sirgiovanni, A. Cistaro and M.C. Valentini
American Journal of Neuroradiology April 2012, 33 (4) 733-739; DOI: https://doi.org/10.3174/ajnr.A2855
G. Carrara
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C. Carapelli
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F. Venturi
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M.M. Ferraris
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L. Lequio
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A. Chiò
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A. Calvo
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S. Sirgiovanni
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A. Cistaro
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Article Information

vol. 33 no. 4 733-739
DOI 
https://doi.org/10.3174/ajnr.A2855
PubMed 
22194369

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received June 8, 2011
  • Accepted after revision July 27, 2011
  • Published online April 10, 2012.

Copyright & Usage 
© 2012 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. G. Carraraa,
  2. C. Carapellia,
  3. F. Venturia,
  4. M.M. Ferrarisa,
  5. L. Lequioa,
  6. A. Chiòb,
  7. A. Calvob,
  8. S. Sirgiovannia,
  9. A. Cistaroc and
  10. M.C. Valentinia
  1. aFrom the Neuroradiology Department (G.C., C.C., F.V., M.M.F., L.L., S.S., M.C.V.) of CTO Hospital, Torino, Italy
  2. bALS Center, Department of Neuroscience (A. Chiò, A. Calvo), University of Torino and AOU San Giovanni Battista, Torino, Italy
  3. cPositron Emission Tomography Center (A. Cistaro), IRMET S.p.A., Torino, Italy.
  1. Please address correspondence to Giovanna Carrara, MD, Department of Neuroradiology, CTO Hospital, Via Zuretti 29, 10126, Torino, Italy; e-mail: giovac26{at}gmail.com
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  • Spinal Cord Imaging in Amyotrophic Lateral Sclerosis: Historical Concepts—Novel Techniques
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G. Carrara, C. Carapelli, F. Venturi, M.M. Ferraris, L. Lequio, A. Chiò, A. Calvo, S. Sirgiovanni, A. Cistaro, M.C. Valentini
A Distinct MR Imaging Phenotype in Amyotrophic Lateral Sclerosis: Correlation between T1 Magnetization Transfer Contrast Hyperintensity along the Corticospinal Tract and Diffusion Tensor Imaging Analysis
American Journal of Neuroradiology Apr 2012, 33 (4) 733-739; DOI: 10.3174/ajnr.A2855

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A Distinct MR Imaging Phenotype in Amyotrophic Lateral Sclerosis: Correlation between T1 Magnetization Transfer Contrast Hyperintensity along the Corticospinal Tract and Diffusion Tensor Imaging Analysis
G. Carrara, C. Carapelli, F. Venturi, M.M. Ferraris, L. Lequio, A. Chiò, A. Calvo, S. Sirgiovanni, A. Cistaro, M.C. Valentini
American Journal of Neuroradiology Apr 2012, 33 (4) 733-739; DOI: 10.3174/ajnr.A2855
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Cited By...

  • A distinct imaging phenotype in amyotrophic lateral sclerosis confidently detected on T1 MTC
  • Corticospinal Tract MR Signal-Intensity Pseudonormalization on Magnetization Transfer Contrast Imaging: A Potential Pitfall in the Interpretation of the Advanced Compromise of Upper Motor Neurons in Amyotrophic Lateral Sclerosis
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Neuroimaging in Amyotrophic Lateral Sclerosis
    Martin R Turner, Federica Agosta, Peter Bede, Varan Govind, Dorothée Lulé, Esther Verstraete
    Biomarkers in Medicine 2012 6 3
  • Assessment of the upper motor neuron in amyotrophic lateral sclerosis
    William Huynh, Neil G. Simon, Julian Grosskreutz, Martin R. Turner, Steve Vucic, Matthew C. Kiernan
    Clinical Neurophysiology 2016 127 7
  • Multi-Parametric Spinal Cord MRI as Potential Progression Marker in Amyotrophic Lateral Sclerosis
    Mohamed-Mounir El Mendili, Julien Cohen-Adad, Mélanie Pelegrini-Issac, Serge Rossignol, Régine Morizot-Koutlidis, Véronique Marchand-Pauvert, Caroline Iglesias, Sina Sangari, Rose Katz, Stéphane Lehericy, Habib Benali, Pierre-François Pradat, Cedric Raoul
    PLoS ONE 2014 9 4
  • Spinal Cord Imaging in Amyotrophic Lateral Sclerosis: Historical Concepts—Novel Techniques
    Mohamed Mounir El Mendili, Giorgia Querin, Peter Bede, Pierre-François Pradat
    Frontiers in Neurology 2019 10
  • Usefulness of SWI for the Detection of Iron in the Motor Cortex in Amyotrophic Lateral Sclerosis
    Yuko Adachi, Noriko Sato, Yuko Saito, Yukio Kimura, Yasuhiro Nakata, Kimiteru Ito, Kouhei Kamiya, Hiroshi Matsuda, Tadashi Tsukamoto, Masahumi Ogawa
    Journal of Neuroimaging 2015 25 3
  • Emerging Magnetic Resonance Imaging Techniques and Analysis Methods in Amyotrophic Lateral Sclerosis
    Andrew W. Barritt, Matt C. Gabel, Mara Cercignani, P. Nigel Leigh
    Frontiers in Neurology 2018 9
  • Diffusion tensor MRI of the corpus callosum in amyotrophic lateral sclerosis
    Molly C. Chapman, Laura Jelsone‐Swain, Timothy D. Johnson, Kirsten L. Gruis, Robert C. Welsh
    Journal of Magnetic Resonance Imaging 2014 39 3
  • Role of PET and SPECT in the Study of Amyotrophic Lateral Sclerosis
    Angelina Cistaro, Vincenzo Cuccurullo, Natale Quartuccio, Marco Pagani, Maria Consuelo Valentini, Luigi Mansi
    BioMed Research International 2014 2014
  • Is magnetic resonance imaging a plausible biomarker for upper motor neuron degeneration in amyotrophic lateral sclerosis/primary lateral sclerosis or merely a useful paraclinical tool to exclude mimic syndromes? A critical review of imaging applicability in clinical routine
    Antonio José da Rocha, Antonio Carlos Martins Maia Júnior
    Arquivos de Neuro-Psiquiatria 2012 70 7
  • Multimodal tract-based analysis in ALS patients at 7T: A specific white matter profile?
    Esther Verstraete, Daniel L. Polders, René C. W. Mandl, Martijn P. Van Den Heuvel, Jan H. Veldink, Peter Luijten, Leonard H. Van Den Berg, Johannes Hoogduin
    Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 2014 15 1-2

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