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Research ArticleAdult Brain
Open Access

Comparative Study of MRI Biomarkers in the Substantia Nigra to Discriminate Idiopathic Parkinson Disease

N. Pyatigorskaya, B. Magnin, M. Mongin, L. Yahia-Cherif, R. Valabregue, D. Arnaldi, C. Ewenczyk, C. Poupon, M. Vidailhet and S. Lehéricy
American Journal of Neuroradiology August 2018, 39 (8) 1460-1467; DOI: https://doi.org/10.3174/ajnr.A5702
N. Pyatigorskaya
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
bUMR S 1127, CNRS UMR 7225 (N.P., B.M., M.M., L.Y.-C., M.V., S.L.), Sorbonne University, Paris, France
cService de neuroradiologie (N.P., B.M., S.L.)
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  • ORCID record for N. Pyatigorskaya
B. Magnin
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
bUMR S 1127, CNRS UMR 7225 (N.P., B.M., M.M., L.Y.-C., M.V., S.L.), Sorbonne University, Paris, France
cService de neuroradiologie (N.P., B.M., S.L.)
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M. Mongin
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
bUMR S 1127, CNRS UMR 7225 (N.P., B.M., M.M., L.Y.-C., M.V., S.L.), Sorbonne University, Paris, France
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L. Yahia-Cherif
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
bUMR S 1127, CNRS UMR 7225 (N.P., B.M., M.M., L.Y.-C., M.V., S.L.), Sorbonne University, Paris, France
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R. Valabregue
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
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D. Arnaldi
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
eClinical Neurology (D.A.), Department of Neuroscience, University of Genoa, Genoa, Italy
gCentre d'Investigation Clinique (D.A., M.V.), Hôpital Pitié-Salpêtrière, Paris, France.
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C. Ewenczyk
dDépartement des Maladies du Système Nerveux (C.E., M.V.), Clinique des mouvements anormaux, Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Paris, France
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C. Poupon
fNeuroSpin (C.P.), Commissariat à l'Energie Atomique, Gif-Sur-Yvette, France
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M. Vidailhet
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
bUMR S 1127, CNRS UMR 7225 (N.P., B.M., M.M., L.Y.-C., M.V., S.L.), Sorbonne University, Paris, France
dDépartement des Maladies du Système Nerveux (C.E., M.V.), Clinique des mouvements anormaux, Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Paris, France
gCentre d'Investigation Clinique (D.A., M.V.), Hôpital Pitié-Salpêtrière, Paris, France.
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S. Lehéricy
aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
bUMR S 1127, CNRS UMR 7225 (N.P., B.M., M.M., L.Y.-C., M.V., S.L.), Sorbonne University, Paris, France
cService de neuroradiologie (N.P., B.M., S.L.)
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Article Information

vol. 39 no. 8 1460-1467
DOI 
https://doi.org/10.3174/ajnr.A5702
PubMed 
29954816

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received January 10, 2018
  • Accepted after revision April 29, 2018
  • Published online August 14, 2018.

Copyright & Usage 
© 2018 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. N. Pyatigorskayaa,b,c,
  2. B. Magnina,b,c,
  3. M. Mongina,b,
  4. L. Yahia-Cherifa,b,
  5. R. Valabreguea,
  6. D. Arnaldia,e,g,
  7. C. Ewenczykd,
  8. C. Pouponf,
  9. M. Vidailheta,b,d,g and
  10. S. Lehéricya,b,c
  1. aFrom the Institut du Cerveau et de la Moelle épinière (N.P., B.M., M.M., L.Y.-C., R.V., D.A., M.V., S.L.), Centre de NeuroImagerie de Recherche, Paris, France
  2. bUMR S 1127, CNRS UMR 7225 (N.P., B.M., M.M., L.Y.-C., M.V., S.L.), Sorbonne University, Paris, France
  3. cService de neuroradiologie (N.P., B.M., S.L.)
  4. dDépartement des Maladies du Système Nerveux (C.E., M.V.), Clinique des mouvements anormaux, Assistance Publique Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Paris, France
  5. eClinical Neurology (D.A.), Department of Neuroscience, University of Genoa, Genoa, Italy
  6. fNeuroSpin (C.P.), Commissariat à l'Energie Atomique, Gif-Sur-Yvette, France
  7. gCentre d'Investigation Clinique (D.A., M.V.), Hôpital Pitié-Salpêtrière, Paris, France.
  1. Please address correspondence to Nadya Pyatigorskaya, MD, PhD, CENIR, ICM, Hôpital Pitié-Salpêtrière 47-83 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France; e-mail: nadya.pyatigorskaya{at}gmail.com; @nadya.pya
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N. Pyatigorskaya, B. Magnin, M. Mongin, L. Yahia-Cherif, R. Valabregue, D. Arnaldi, C. Ewenczyk, C. Poupon, M. Vidailhet, S. Lehéricy
Comparative Study of MRI Biomarkers in the Substantia Nigra to Discriminate Idiopathic Parkinson Disease
American Journal of Neuroradiology Aug 2018, 39 (8) 1460-1467; DOI: 10.3174/ajnr.A5702

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Comparative Study of MRI Biomarkers in the Substantia Nigra to Discriminate Idiopathic Parkinson Disease
N. Pyatigorskaya, B. Magnin, M. Mongin, L. Yahia-Cherif, R. Valabregue, D. Arnaldi, C. Ewenczyk, C. Poupon, M. Vidailhet, S. Lehéricy
American Journal of Neuroradiology Aug 2018, 39 (8) 1460-1467; DOI: 10.3174/ajnr.A5702
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  • Parkinson Disease Propagation Using MRI Biomarkers and Partial Least Squares Path Modeling
  • Crossref (22)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Combined Visualization of Nigrosome-1 and Neuromelanin in the Substantia Nigra Using 3T MRI for the Differential Diagnosis of Essential Tremor and de novo Parkinson's Disease
    Lirong Jin, Jian Wang, Changpeng Wang, Danlan Lian, Ying Zhou, Yong Zhang, Minzhi Lv, Yuanfang Li, Zhen Huang, Xiaoqin Cheng, Guoqiang Fei, Kai Liu, Mengsu Zeng, Chunjiu Zhong
    Frontiers in Neurology 2019 10
  • Toxic Feedback Loop Involving Iron, Reactive Oxygen Species, α-Synuclein and Neuromelanin in Parkinson’s Disease and Intervention with Turmeric
    Zuné Jansen van Rensburg, Shameemah Abrahams, Soraya Bardien, Colin Kenyon
    Molecular Neurobiology 2021 58 11
  • The Role of Magnetic Resonance Imaging for the Diagnosis of Atypical Parkinsonism
    Lydia Chougar, Nadya Pyatigorskaya, Bertrand Degos, David Grabli, Stéphane Lehéricy
    Frontiers in Neurology 2020 11
  • Iron Content in Deep Gray Matter as a Function of Age Using Quantitative Susceptibility Mapping: A Multicenter Study
    Yan Li, Sean K. Sethi, Chunyan Zhang, Yanwei Miao, Kiran Kumar Yerramsetty, Vinay Kumar Palutla, Sara Gharabaghi, Chengyan Wang, Naying He, Jingliang Cheng, Fuhua Yan, Ewart Mark Haacke
    Frontiers in Neuroscience 2021 14
  • Modern Brainstem MRI Techniques for the Diagnosis of Parkinson's Disease and Parkinsonisms
    Germain Arribarat, Amaury De Barros, Patrice Péran
    Frontiers in Neurology 2020 11
  • A distinct neuromelanin magnetic resonance imaging pattern in parkinsonian multiple system atrophy
    Rita Moiron Simões, Ana Castro Caldas, Joana Grilo, Daisy Correia, Carla Guerreiro, Patrícia Pita Lobo, Anabela Valadas, Marguerita Fabbri, Leonor Correia Guedes, Miguel Coelho, Mario Miguel Rosa, Joaquim J. Ferreira, Sofia Reimão
    BMC Neurology 2020 20 1
  • A fully automated approach involving neuroimaging and deep learning for Parkinson’s disease detection and severity prediction
    Çağatay Berke Erdaş, Emre Sümer
    PeerJ Computer Science 2023 9
  • Imaging in Movement Disorders: Imaging Methodology and Applications in Parkinson's Disease
    Rosa De Micco, Antonio Russo, Alessandro Tessitore
    2018 141
  • Morphological analysis of subcortical structures for assessment of cognitive dysfunction in Parkinson’s disease using multi-atlas based segmentation
    S. Sivaranjini, C. M. Sujatha
    Cognitive Neurodynamics 2021 15 5
  • Quantitative iron–neuromelanin MRI associates with motor severity in Parkinson's disease and matches radiological disease classification
    Septian Hartono, Robert Chun Chen, Thomas Welton, An Sen Tan, Weiling Lee, Peik Yen Teh, Celeste Chen, Wenlu Hou, Wei Ping Tham, Ee Wei Lim, Kumar M. Prakash, Yao-Chia Shih, Kuan Jin Lee, Louis C. S. Tan, Eng King Tan, Ling Ling Chan
    Frontiers in Aging Neuroscience 2023 15

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