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OtherNeuroimaging Physics/Functional Neuroimaging/CT and MRI Technology

Recommended Resting-State fMRI Acquisition and Preprocessing Steps for Preoperative Mapping of Language and Motor and Visual Areas in Adult and Pediatric Patients with Brain Tumors and Epilepsy

V.A. Kumar, J. Lee, H.-L. Liu, J.W. Allen, C.G. Filippi, A.I. Holodny, K. Hsu, R. Jain, M.P. McAndrews, K.K. Peck, G. Shah, J.S. Shimony, S. Singh, M. Zeineh, J. Tanabe, B. Vachha, A. Vossough, K. Welker, C. Whitlow, M. Wintermark, G. Zaharchuk and H.I. Sair
American Journal of Neuroradiology February 2024, 45 (2) 139-148; DOI: https://doi.org/10.3174/ajnr.A8067
V.A. Kumar
aFrom the The University of Texas MD Anderson Cancer Center (V.A.K., J.L., H.-L.L., M.W.), Houston, Texas
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  • ORCID record for V.A. Kumar
J. Lee
aFrom the The University of Texas MD Anderson Cancer Center (V.A.K., J.L., H.-L.L., M.W.), Houston, Texas
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H.-L. Liu
aFrom the The University of Texas MD Anderson Cancer Center (V.A.K., J.L., H.-L.L., M.W.), Houston, Texas
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J.W. Allen
bEmory University (J.W.A.), Atlanta, Georgia
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C.G. Filippi
cTufts University (C.G.F.), Boston, Massachusetts
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A.I. Holodny
dMemorial Sloan Kettering Cancer Center (A.I.H., K.K.P.), New York, New York
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K. Hsu
eNew York University (K.H., R.J.), New York, New York
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R. Jain
eNew York University (K.H., R.J.), New York, New York
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M.P. McAndrews
fUniversity of Toronto (M.P.M.), Toronto, Ontario, Canada
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K.K. Peck
dMemorial Sloan Kettering Cancer Center (A.I.H., K.K.P.), New York, New York
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G. Shah
gUniversity of Michigan (G.S.), Ann Arbor, Michigan
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J.S. Shimony
hWashington University School of Medicine (J.S.S.), St. Louis, Missouri
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S. Singh
iUniversity of Texas Southwestern Medical Center (S.S.), Dallas, Texas
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M. Zeineh
jStanford University (M.Z., G.Z.), Palo Alto, California
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J. Tanabe
kUniversity of Colorado (J.T.), Aurora, Colorado
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B. Vachha
lUniversity of Massachusetts (B.V.), Worcester, Massachusetts
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A. Vossough
mChildren’s Hospital of Philadelphia, University of Pennsylvania (A.V.), Philadelphia, Pennsylvania
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K. Welker
nMayo Clinic (K.W.), Rochester, Minnesota
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C. Whitlow
oWake Forest University (C.W.), Winston-Salem, North Carolina
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M. Wintermark
aFrom the The University of Texas MD Anderson Cancer Center (V.A.K., J.L., H.-L.L., M.W.), Houston, Texas
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G. Zaharchuk
jStanford University (M.Z., G.Z.), Palo Alto, California
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H.I. Sair
pJohns Hopkins University (H.I.S.), Baltimore, Maryland.
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    Table 1:

    Resting-state fMRI acquisition parameters

    Acquisition ParametersRecommended
    Length of scanMinimum of 6 minutes
    Eye statusEO-F
    Order of rs-fMRI vs tb-fMRIrs-fMRI before tb-fMRI
    TR≤2 Seconds
    Physiologic noise source monitoringOptional
    IV contrast administrationAfter rs-fMRI
    Scanner field strength3T or higher
    • View popup
    Table 2:

    Resting-state fMRI preprocessing steps

    Preprocessing StepsRecommended
    Motion correctionYes, for SBC and ICA
    STCOptional for TR ≤2 Recommended for TR >2 for SBC and ICA
    Elimination of systematic odd-even slice-intensity differencesOptional
    DespikingYes, for SBC only
    Volume censoring/scrubbingYes, for SBC and ICA
    Linear detrendingOptional
    Nuisance regression: CSF/white matterYes, for SBC only
    Nuisance regression: head motionYes, for SBC and ICA
    Nuisance regression: global signalOptional
    Temporal filteringYes, bandpass filtering for SBC and ICA
    Spatial smoothingYes, with smoothing kernel at twice the voxel size for SBC and ICA
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American Journal of Neuroradiology: 45 (2)
American Journal of Neuroradiology
Vol. 45, Issue 2
1 Feb 2024
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V.A. Kumar, J. Lee, H.-L. Liu, J.W. Allen, C.G. Filippi, A.I. Holodny, K. Hsu, R. Jain, M.P. McAndrews, K.K. Peck, G. Shah, J.S. Shimony, S. Singh, M. Zeineh, J. Tanabe, B. Vachha, A. Vossough, K. Welker, C. Whitlow, M. Wintermark, G. Zaharchuk, H.I. Sair
Recommended Resting-State fMRI Acquisition and Preprocessing Steps for Preoperative Mapping of Language and Motor and Visual Areas in Adult and Pediatric Patients with Brain Tumors and Epilepsy
American Journal of Neuroradiology Feb 2024, 45 (2) 139-148; DOI: 10.3174/ajnr.A8067

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Resting-State fMRI in Tumors and Epilepsy
V.A. Kumar, J. Lee, H.-L. Liu, J.W. Allen, C.G. Filippi, A.I. Holodny, K. Hsu, R. Jain, M.P. McAndrews, K.K. Peck, G. Shah, J.S. Shimony, S. Singh, M. Zeineh, J. Tanabe, B. Vachha, A. Vossough, K. Welker, C. Whitlow, M. Wintermark, G. Zaharchuk, H.I. Sair
American Journal of Neuroradiology Feb 2024, 45 (2) 139-148; DOI: 10.3174/ajnr.A8067
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