Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBrain
Open Access

The Effect of Transcatheter Injections on Cell Viability and Cytokine Release of Mononuclear Cells

R. El Khoury, V. Misra, S. Sharma, C.S. Cox, P. Walker, J.C. Grotta, A. Gee, S. Suzuki and S.I. Savitz
American Journal of Neuroradiology September 2010, 31 (8) 1488-1492; DOI: https://doi.org/10.3174/ajnr.A2092
R. El Khoury
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
V. Misra
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Sharma
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C.S. Cox
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P. Walker
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J.C. Grotta
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Gee
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Suzuki
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.I. Savitz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    Stem Cell Therapies as an Emerging Paradigm in Stroke Participants. Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke. Stroke 2009;40:510–15. Epub 2008 Dec 18
    Abstract/FREE Full Text
  2. 2.↵
    1. Savitz SI,
    2. Misra V
    . Launching intravenous bone marrow cell trials for acute stroke. Regen Med 2009;4:639–41
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Wechsler LR
    . Clinical trials of stroke therapy: which cells, which patients? Stroke 2009;40:S149–151
    FREE Full Text
  4. 4.↵
    1. Savitz SI,
    2. Dinsmore J,
    3. Wu J,
    4. et al
    . Neurotransplantation of fetal porcine cells in patients with basal ganglia infarcts: a preliminary safety and feasibility study. Cerebrovasc Dis 2005;20:101–07
    PubMedWeb of Science
  5. 5.↵
    1. Fischer UM,
    2. Harting MT,
    3. Jimenez F,
    4. et al
    . Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first pass effect. Stem Cells Dev 2008;18:683–92
    CrossRef
  6. 6.↵
    1. Kamiya N,
    2. Ueda M,
    3. Igarashi H,
    4. et al
    . Intra-arterial transplantation of bone marrow mononuclear cells immediately after reperfusion decreases brain injury after focal ischemia in rats. Life Sci 2008;83:433–37
    CrossRefPubMed
  7. 7.↵
    US Food and Drug Administration. Draft Guidance for Industry: Somatic Cell Therapy for Cardiac Disease. March 2009. US Department of Health and Human Services Web site. Vaccines, Blood, and Biologics. http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/CellularandGeneTherapy/ucm164265.htm. Accessed December 9, 2009
  8. 8.↵
    1. Brenneman M,
    2. Sharma S,
    3. Harting M,
    4. et al
    . Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats. J Cereb Blood Flow Metab 2010;30:140–49. Epub 2009 Sep 23
    CrossRefPubMed
  9. 9.↵
    1. Baker AH,
    2. Sica V,
    3. Work LM,
    4. et al
    . Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia. Proc Natl Acad Sci U S A 2007;104:3597–602
    Abstract/FREE Full Text
  10. 10.↵
    1. Lipinski MJ,
    2. Biondi-Zoccai GG,
    3. Abbate A,
    4. et al
    . Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials. J Am Coll Cardiol 2007;50:1761–67
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Correa PL,
    2. Mesquita CT,
    3. Felix RM,
    4. et al
    . Assessment of intra-arterial injected autologous bone marrow mononuclear cell distribution by radioactive labeling in acute ischemic stroke. Clin Nucl Med 2007;32:839–41
    CrossRefPubMed
  12. 12.↵
    1. Harting MT,
    2. Cox CS,
    3. Day MC,
    4. et al
    . Bone marrow-derived mononuclear cell populations in pediatric and adult patients. Cytotherapy 2009;11:480–84
    CrossRefPubMed
  13. 13.↵
    1. Tol M,
    2. Akar AR,
    3. Durdu S,
    4. et al
    . Comparison of different needle diameters and flow rates on bone marrow mononuclear stem cell viability: an ex vivo experimental study. Cytotherapy 2008;10:98–99
    CrossRefPubMed
  14. 14.↵
    1. Yoon W,
    2. Park MS,
    3. Cho KH
    . Low-dose intra-arterial urokinase and aggressive mechanical clot disruption for acute ischemic stroke after failure of intravenous thrombolysis. AJNR Am J Neuroradiol 2010;31:161–64. Epub 2009 Aug 27
    Abstract/FREE Full Text
  15. 15.↵
    1. Sangchot P,
    2. Sharma S,
    3. Chetsawang B,
    4. et al
    . Deferoxamine attenuates iron-induced oxidative stress and prevents mitochondrial aggregation and alpha-synuclein translocation in SK-N-SH cells in culture. Dev Neurosci 2002;24:143–53
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Takahashi M,
    2. Li TS,
    3. Suzuki R,
    4. et al
    . Cytokines produced by bone marrow cells can contribute to functional improvement of the infarcted heart by protecting cardiomyocytes from ischemic injury. Am J Physiol Heart Circ Physiol 2006;291:H886–93
    Abstract/FREE Full Text
  17. 17.↵
    1. Iihoshi S,
    2. Honmou O,
    3. Houkin K,
    4. et al
    . A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats. Brain Res 2004;1007:1–9
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Heng BC,
    2. Hsu SH,
    3. Cowan CM,
    4. et al
    . Trans-catheter injection induced changes in human bone marrow-derived mesenchymal stem cells. Cell Transplant 2009;18:1111–21. Epub 2009 Jun 22
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 31 (8)
American Journal of Neuroradiology
Vol. 31, Issue 8
1 Sep 2010
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The Effect of Transcatheter Injections on Cell Viability and Cytokine Release of Mononuclear Cells
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
R. El Khoury, V. Misra, S. Sharma, C.S. Cox, P. Walker, J.C. Grotta, A. Gee, S. Suzuki, S.I. Savitz
The Effect of Transcatheter Injections on Cell Viability and Cytokine Release of Mononuclear Cells
American Journal of Neuroradiology Sep 2010, 31 (8) 1488-1492; DOI: 10.3174/ajnr.A2092

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
The Effect of Transcatheter Injections on Cell Viability and Cytokine Release of Mononuclear Cells
R. El Khoury, V. Misra, S. Sharma, C.S. Cox, P. Walker, J.C. Grotta, A. Gee, S. Suzuki, S.I. Savitz
American Journal of Neuroradiology Sep 2010, 31 (8) 1488-1492; DOI: 10.3174/ajnr.A2092
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Abbreviations
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Stem cell therapy in ischemic stroke: Role of IV and intra-arterial therapy
  • Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Fast Contrast-Enhanced 4D MRA and 4D Flow MRI Using Constrained Reconstruction (HYPRFlow): Potential Applications for Brain Arteriovenous Malformations
  • Multimodal CT Provides Improved Performance for Lacunar Infarct Detection
  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire