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Studies to date have shown signal maturation patterns in the pediatric population using various sequences. However, there is a paucity of information about brain maturation patterns of FLAIR signal intensities across the pediatric range. Additionally, intensities vary widely across FLAIR MR imaging scanners. A FLAIR intensity standardization algorithm would be helpful to normalize intensity across large data sets, allowing comparison of FLAIR intensity in different regions and individuals.

Multinodular and vacuolating neuronal tumors (MVNTs) are classified as WHO grade 1 tumors and typically described as “leave me alone” lesions. Less frequent surveillance imaging can be performed based on the longitudinal volumetric stability of these lesions.

Various CTP metrics are used as biomarkers of ischemia and clinical outcomes in some patients undergoing EVT. This post hoc analysis of the Safety and Efficacy of Nerinetide in Subjects Undergoing Endovascular Thrombectomy for Stroke (ESCAPE-NA1) trial shows that patients having undergone EVT with baseline small CTP lesion volumes have a better clinical outcome compared with those with larger CTP lesions. However, CTP was not able to elucidate why some patients have poor outcomes despite near-complete recanalization.