- Hemorrhage Volume Drives Early Brain Injury and Outcome in Poor-Grade Aneurysmal SAH
Early brain injury (radiologically defined by global cerebral edema) is a major determinant of clinical outcome in poor-grade aneurysmal SAH. In this retrospective study of 400 patients with poor-grade aneurysmal SAH, it was shown that intracerebral hemorrhage volume independently predicted global cerebral edema and long-term outcome, intraventricular hemorrhage volume predicted mortality and long-term outcome, and SAH volume predicted long-term clinical outcome.
- A Clinical and Imaging Fused Deep Learning Model Matches Expert Clinician Prediction of 90-Day Stroke Outcomes
The authors in this study used a deep learning-based predictive model (DLPD) that incorporated DWI and clinical data from the acute period to predict 90-day mRS outcomes and compared its predictions with those made by physicians. The results showed that the clinical and imaging fused deep learning model is noninferior to expert physicians in predicting specific mRS outcomes and unfavorable prognoses.
- CTA and CTP for Detecting Distal Medium Vessel Occlusions: A Systematic Review and Meta-analysis
This systematic review and meta-analysis aimed to compare the diagnostic test accuracy for CTA and CTP in the detection of distal medium vessel occlusion. The study found consistent evidence for a higher sensitivity in detecting distal medium vessel occlusion, particularly in arteries beyond the M2 segment of MCA, with multiphase CTA or CTP compared with single-phase CTA.
- Prevalence and Characteristics of Intracranial Aneurysms in Hereditary Hemorrhagic Telangiectasia
In this retrospective study, the authors evaluated the prevalence and characteristics of intracranial aneurysms in patients with hereditary hemorrhagic telangiectasia with brain vascular malformations. In their study cohort of 180 patients with HHT and brain vascular malformations, the authors demonstrated that the prevalence of intracranial aneurysm in hereditary hemorrhagic telangiectasia is comparable with that in the general population without clear association with shunting brain vascular malformations.
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