Neuropathology for the Neuroradiologist: Plaques and Tangles

F.J. Wippold; N. Cairns; K. Vo; D.M. Holtzman; J.C. Morris

doi:10.3174/ajnr.A0781

OtherPATHOLOGY REVIEW

Neuropathology for the Neuroradiologist: Plaques and Tangles

F.J. Wippold, N. Cairns, K. Vo, D.M. Holtzman and J.C. Morris

American Journal of Neuroradiology January 2008, 29 (1) 18-22; DOI: https://doi.org/10.3174/ajnr.A0781

F.J. Wippold II

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

N. Cairns

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

K. Vo

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

D.M. Holtzman

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

J.C. Morris

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
Info & Metrics
Responses
References
PDF

Article Information

vol. 29 no. 1 18-22

DOI

https://doi.org/10.3174/ajnr.A0781

PubMed

17925367

Published By

American Journal of Neuroradiology

Print ISSN

0195-6108

Online ISSN

1936-959X

History

Received June 20, 2007
Accepted after revision June 27, 2007
Published online January 11, 2008.

Author Information

F.J. Wippold IIa,b,c,d,
N. Cairnsd,e,f,
K. Voa,b,
D.M. Holtzmand,f,g and
J.C. Morrisd,g

^aMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Mo
^bDepartment of Radiology, Barnes-Jewish Hospital South, St. Louis, Mo
^cDepartment of Radiology/Nuclear Medicine, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md
^dAlzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Mo
^eNeuropathology Division, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Mo
^fHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Mo
^gDepartment of Neurology and Neurological Surgery, Washington University School of Medicine, St. Louis, Mo

Please address correspondence to: Franz J. Wippold II, MD, Neuroradiology Section, Mallinckrodt Institute of Radiology, Washington University Medical Center, 510 South Kingshighway Blvd, St. Louis, MO 63110; e-mail: wippoldf{at}wustl.edu

View Full Text

Altmetrics

Cited By...

40 Citations
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Review on Alzheimer's disease: Inhibition of amyloid beta and tau tangle formation

Hossein Ashrafian, Elaheh Hadi Zadeh, Rizwan Hasan Khan

International Journal of Biological Macromolecules 2021 167
Dementia As a Cultural Metaphor

H. Zeilig

The Gerontologist 2014 54 2
Extracellular protein components of amyloid plaques and their roles in Alzheimer’s disease pathology

M. Mahafuzur Rahman, Christofer Lendel

Molecular Neurodegeneration 2021 16 1
Functional outcome after convulsive status epilepticus

Stéphane Legriel, Elie Azoulay, Matthieu Resche-Rigon, Virginie Lemiale, Bruno Mourvillier, Achille Kouatchet, Gilles Troché, Manuel Wolf, Richard Galliot, Géraldine Dessertaine, Danièle Combaux, Frederic Jacobs, Pascal Beuret, Bruno Megarbane, Pierre Carli, Yves Lambert, Fabrice Bruneel, Jean-Pierre Bedos

Critical Care Medicine 2010 38 12
Multimodality Review of Amyloid-related Diseases of the Central Nervous System

Michelle M. Miller-Thomas, Adam L. Sipe, Tammie L. S. Benzinger, Jonathan McConathy, Sarah Connolly, Katherine E. Schwetye

RadioGraphics 2016 36 4
Safety and Pharmacology of a Single Intravenous Dose of Ponezumab in Subjects With Mild-to-Moderate Alzheimer Disease

Jaren W. Landen, Qinying Zhao, Sharon Cohen, Michael Borrie, Michael Woodward, Clare B. Billing, Kelly Bales, Christine Alvey, Fred McCush, Jerry Yang, James W. Kupiec, Martin M. Bednar

Clinical Neuropharmacology 2013 36 1
The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer’s Disease

Yanuar Alan Sulistio, Klaus Heese

Molecular Neurobiology 2016 53 2
Advancements in the development of multi-target directed ligands for the treatment of Alzheimer’s disease

Naveen Kumar, Vijay Kumar, Piyush Anand, Vinay Kumar, Ashish Ranjan Dwivedi, Vinod Kumar

Bioorganic & Medicinal Chemistry 2022 61
Nano-HPLC–MS analysis of phospholipids in cerebrospinal fluid of Alzheimer’s disease patients—a pilot study

M. Kosicek, S. Kirsch, R. Bene, Z. Trkanjec, M. Titlic, L. Bindila, J. Peter-Katalinic, S. Hecimovic

Analytical and Bioanalytical Chemistry 2010 398 7-8
Multiple‐dose ponezumab for mild‐to‐moderate Alzheimer's disease: Safety and efficacy

Jaren W. Landen, Sharon Cohen, Clare B. Billing, Carol Cronenberger, Scot Styren, Aaron H. Burstein, Catherine Sattler, Jae‐Hong Lee, Clifford R. Jack, Kejal Kantarci, Pamela F. Schwartz, William T. Duggan, Qinying Zhao, Ken Sprenger, Martin M. Bednar, Brendon Binneman

Alzheimer's & Dementia: Translational Research & Clinical Interventions 2017 3 3
Diabetes Mellitus

Suzanne M. de la Monte

2019 1128
Activity of Selected Group of Monoterpenes in Alzheimer’s Disease Symptoms in Experimental Model Studies—A Non-Systematic Review

Karolina Wojtunik-Kulesza, Monika Rudkowska, Kamila Kasprzak-Drozd, Anna Oniszczuk, Kinga Borowicz-Reutt

International Journal of Molecular Sciences 2021 22 14
In vivo parahippocampal white matter pathology as a biomarker of disease progression to Alzheimer's disease

Ana Solodkin, E. Elinor Chen, Gary W. Van Hoesen, Lennart Heimer, Ahmed Shereen, Frithjof Kruggel, James Mastrianni

Journal of Comparative Neurology 2013 521 18
Gaps and spaces: Representations of dementia in contemporary British poetry

Hannah Zeilig

Dementia 2014 13 2
Amyloid β and tau pathology in brains of aged pinniped species (sea lion, seal, and walrus)

Yuta Takaichi, James K. Chambers, Kei Takahashi, Yoshiyuki Soeda, Riki Koike, Etsuko Katsumata, Chiaki Kita, Fuko Matsuda, Makoto Haritani, Akihiko Takashima, Hiroyuki Nakayama, Kazuyuki Uchida

Acta Neuropathologica Communications 2021 9 1
Label-Free Infrared Spectroscopic Imaging Reveals Heterogeneity of β-Sheet Aggregates in Alzheimer’s Disease

Matthew P. Confer, Brooke M. Holcombe, Abigail G. Foes, John M. Holmquist, Savannah C. Walker, Sanghamitra Deb, Ayanjeet Ghosh

The Journal of Physical Chemistry Letters 2021 12 39
Scope of β-Secretase (BACE1)-Targeted Therapy in Alzheimer’s Disease: Emphasizing the Flavonoid Based Natural Scaffold for BACE1 Inhibition

Sucharita Das, Swaha Sengupta, Sandipan Chakraborty

ACS Chemical Neuroscience 2020 11 21
ACR Appropriateness Criteria® Dementia

Gul Moonis, Rathan M. Subramaniam, Anna Trofimova, Judah Burns, Julie Bykowski, Santanu Chakraborty, Kathryn Holloway, Luke N. Ledbetter, Ryan K. Lee, Jeffrey S. Pannell, Jeffrey M. Pollock, William J. Powers, Robert P. Roca, Joshua M. Rosenow, Robert Y. Shih, Pallavi S. Utukuri, Amanda S. Corey

Journal of the American College of Radiology 2020 17 5
Quantitative Susceptibility Mapping of the Hippocampal Fimbria in Alzheimer's Disease

Chun Ki Franklin Au, Jill Abrigo, Chunlei Liu, Wanting Liu, Jack Lee, Lisa Wing Chi Au, Queenie Chan, Sirong Chen, Eric Yim Lung Leung, Chi Lai Ho, Ho Ko, Vincent Chung Tong Mok, Weitian Chen

Journal of Magnetic Resonance Imaging 2021 53 6
Multitargeted drug development: Discovery and profiling of dihydroxy substituted 1-aza-9-oxafluorenes as lead compounds targeting Alzheimer disease relevant kinases

Volkmar Tell, Max Holzer, Lydia Herrmann, Kazem Ahmed Mahmoud, Christoph Schächtele, Frank Totzke, Andreas Hilgeroth

Bioorganic & Medicinal Chemistry Letters 2012 22 22
Age related neurodegenerative Alzheimer’s disease: Usage of traditional herbs in therapeutics

Abhishek Singh, Sindhu Agarwal, Sarika Singh

Neuroscience Letters 2020 717
Heterogeneity of Amyloid Binding in Cognitively Impaired Patients Consecutively Recruited from a Memory Clinic: Evaluating the Utility of Quantitative 18F-Flutemetamol PET-CT in Discrimination of Mild Cognitive Impairment from Alzheimer’s Disease and Other Dementias

Yi-Wen Bao, Anson C.M. Chau, Patrick Ka-Chun Chiu, Yat Fung Shea, Joseph S.K. Kwan, Felix Hon Wai Chan, Henry Ka-Fung Mak

Journal of Alzheimer's Disease 2021 79 2
Novel aspects in structure–activity relationships of profiled 1-aza-9-oxafluorenes as inhibitors of Alzheimer's disease-relevant kinases cdk1, cdk5 and gsk3β

Volkmar Tell, Kazem Ahmed Mahmoud, Kanin Wichapong, Christoph Schächtele, Frank Totzke, Wolfgang Sippl, Andreas Hilgeroth

MedChemComm 2012 3 11
Analysis of Technological Developments in the Treatment of Alzheimer’s Disease through Patent Documents

Karinne Marieta Carvalho, Eduardo Winter, Adelaide Maria de Souza Antunes

Intelligent Information Management 2015 07 05
Modulating Microenvironments for Treating Glioblastoma

LaDeidra Monet Roberts, Jennifer Munson

Current Tissue Microenvironment Reports 2020 1 3
Anti-amyloidogenic indolizino[3,2-c]quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β

Kyeonghwan Kim, Jeong Hwa Lee, Sunmi Kim, Songmin Lee, Donghee Lee, Hye Yun Kim, Ikyon Kim, YoungSoo Kim

RSC Medicinal Chemistry 2021 12 11
Colocalization of β-Sheets and Carotenoids in Aβ Plaques Revealed with Multimodal Spatially Resolved Vibrational Spectroscopy

Ana Pacheco de Oliveira, William Chase, Matthew P. Confer, Savannah Walker, Divya Baghel, Ayanjeet Ghosh

The Journal of Physical Chemistry B 2024 128 1
Intracranial Hemorrhage in Hospitalized Patients: An Infrequently Studied Condition with High Mortality

Andrea Loggini, Victor J. Del Brutto, Faten El Ammar, Zachary B. Bulwa, Faddi Saleh Velez, Cedric McKoy, Raisa C. Martinez, James Brorson, Fernando D. Goldenberg, Agnieszka A. Ardelt

Neurocritical Care 2020 33 3
Targeting gut-brain axis by dietary flavonoids ameliorate aging-related cognition decline: Evidences and mechanisms

Zhongxing Chu, Shuai Han, Yi Luo, Yaping Zhou, Lingfeng Zhu, Feijun Luo

Critical Reviews in Food Science and Nutrition 2024 64 28
Senile plaques and phosphorylated tau deposition in a super-aged rhesus monkey (<i>Macaca mulatta</i>)

Susumu IWAIDE, Yutaro NAKAYAMA, James K CHAMBERS, Kazuyuki UCHIDA, Daisuke NAKAGAWA, Yumi YAMANASHI, Haruna BANDO, Tomoaki MURAKAMI

Journal of Veterinary Medical Science 2023 85 12
Distinctive Features of Histochemical and Immunohistochemical Techniques for Amyloid Plaque Detection in the Human Cerebral Cortex

V. V. Guselnikova, M. V. Antipova, E. A. Fedorova, A. E. Safray, A. A. Rukavishnikova, E. V. Mikhailova, D. E. Korzhevskii

Journal of Anatomy and Histopathology 2019 8 2
Screening of BACE1 inhibitors with antiamyloidogenic activity: A study of flavonoids and flavonoid derivatives

Sucharita Das, Suchismita Datta, Agamani Ghosal, Nibedita Ray Chaudhuri, Geetanjali Sundaram, Soumalee Basu

Neuroscience Letters 2023 792
The role of oxidative stress in the development of Alzheimer's disease

V. N. Nikolenko, N. A. Rizaeva, K. V. Bulygin, V. M. Anokhina, A. A. Bolotskaya

Neurology, Neuropsychiatry, Psychosomatics 2022 14 4
Beta-Amyloid Related Neurodegenerative and Neurovascular Diseases: Potential Implications for Transfusion Medicine

Ryan T. Muir, Jeannie L. Callum, Amy Y.X. Yu, Moira K. Kapral, Richard H. Swartz, Sandra E. Black, Bradley J. MacIntosh, Dean A. Fergusson, Steven Kleinman, Andrew D. Demchuk, Peter K. Stys, Eric E. Smith, Michael D. Hill

Transfusion Medicine Reviews 2024 38 4
Encyclopedia of Gerontology and Population Aging

Hannah Zeilig

2021
Handbook of Neuroengineering

Yu-Hang Liu, Yu Xu, Nitish Thakor

2022
Encyclopedia of Gerontology and Population Aging

Hannah Zeilig

2020
Handbook of Neuroengineering

Yu-Hang Liu, Yu Xu, Nitish V. Thakor

2023
Health Care for People with Intellectual and Developmental Disabilities across the Lifespan

Norberto Alvarez

2016
The MIR-NAT MAPT-AS1 does not regulate Tau expression in human neurons

Rafaela Policarpo, Leen Wolfs, Saul Martínez-Montero, Lina Vandermeulen, Ines Royaux, Gert Van Peer, Pieter Mestdagh, Bart De Strooper, Annerieke Sierksma, Constantin d’Ydewalle, Efthimios M. C. Skoulakis

PLOS ONE 2025 20 1

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 29, Issue 1

January 2008

Table of Contents
Index by author

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Neuropathology for the Neuroradiologist: Plaques and Tangles

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

F.J. Wippold, N. Cairns, K. Vo, D.M. Holtzman, J.C. Morris

Neuropathology for the Neuroradiologist: Plaques and Tangles

American Journal of Neuroradiology Jan 2008, 29 (1) 18-22; DOI: 10.3174/ajnr.A0781

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

Neuropathology for the Neuroradiologist: Plaques and Tangles

F.J. Wippold, N. Cairns, K. Vo, D.M. Holtzman, J.C. Morris

American Journal of Neuroradiology Jan 2008, 29 (1) 18-22; DOI: 10.3174/ajnr.A0781

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Info & Metrics
Responses
References
PDF

No related articles found.

PubMed
Google Scholar

Cited By...

No citing articles found.

Crossref (40)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Review on Alzheimer's disease: Inhibition of amyloid beta and tau tangle formation

Hossein Ashrafian, Elaheh Hadi Zadeh, Rizwan Hasan Khan

International Journal of Biological Macromolecules 2021 167
Dementia As a Cultural Metaphor

H. Zeilig

The Gerontologist 2014 54 2
Extracellular protein components of amyloid plaques and their roles in Alzheimer’s disease pathology

M. Mahafuzur Rahman, Christofer Lendel

Molecular Neurodegeneration 2021 16 1
Functional outcome after convulsive status epilepticus

Stéphane Legriel, Elie Azoulay, Matthieu Resche-Rigon, Virginie Lemiale, Bruno Mourvillier, Achille Kouatchet, Gilles Troché, Manuel Wolf, Richard Galliot, Géraldine Dessertaine, Danièle Combaux, Frederic Jacobs, Pascal Beuret, Bruno Megarbane, Pierre Carli, Yves Lambert, Fabrice Bruneel, Jean-Pierre Bedos

Critical Care Medicine 2010 38 12
Multimodality Review of Amyloid-related Diseases of the Central Nervous System

Michelle M. Miller-Thomas, Adam L. Sipe, Tammie L. S. Benzinger, Jonathan McConathy, Sarah Connolly, Katherine E. Schwetye

RadioGraphics 2016 36 4
Safety and Pharmacology of a Single Intravenous Dose of Ponezumab in Subjects With Mild-to-Moderate Alzheimer Disease

Jaren W. Landen, Qinying Zhao, Sharon Cohen, Michael Borrie, Michael Woodward, Clare B. Billing, Kelly Bales, Christine Alvey, Fred McCush, Jerry Yang, James W. Kupiec, Martin M. Bednar

Clinical Neuropharmacology 2013 36 1
The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer’s Disease

Yanuar Alan Sulistio, Klaus Heese

Molecular Neurobiology 2016 53 2
Advancements in the development of multi-target directed ligands for the treatment of Alzheimer’s disease

Naveen Kumar, Vijay Kumar, Piyush Anand, Vinay Kumar, Ashish Ranjan Dwivedi, Vinod Kumar

Bioorganic & Medicinal Chemistry 2022 61
Nano-HPLC–MS analysis of phospholipids in cerebrospinal fluid of Alzheimer’s disease patients—a pilot study

M. Kosicek, S. Kirsch, R. Bene, Z. Trkanjec, M. Titlic, L. Bindila, J. Peter-Katalinic, S. Hecimovic

Analytical and Bioanalytical Chemistry 2010 398 7-8
Multiple‐dose ponezumab for mild‐to‐moderate Alzheimer's disease: Safety and efficacy

Jaren W. Landen, Sharon Cohen, Clare B. Billing, Carol Cronenberger, Scot Styren, Aaron H. Burstein, Catherine Sattler, Jae‐Hong Lee, Clifford R. Jack, Kejal Kantarci, Pamela F. Schwartz, William T. Duggan, Qinying Zhao, Ken Sprenger, Martin M. Bednar, Brendon Binneman

Alzheimer's & Dementia: Translational Research & Clinical Interventions 2017 3 3

Main menu

User menu

Search

American Journal of Neuroradiology

Neuropathology for the Neuroradiologist: Plaques and Tangles

Article Information

Author Information

Altmetrics

Cited By...

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

Resources

Multimedia

About Us

American Society of Neuroradiology