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Research ArticleNeurointervention

Image Quality of Low-Dose Cerebral Angiography and Effectiveness of Clinical Implementation on Diagnostic and Neurointerventional Procedures for Intracranial Aneurysms

J. Choi, B. Kim, Y. Choi, N.Y. Shin, J. Jang, H.S. Choi, S.L. Jung and K.J. Ahn
American Journal of Neuroradiology May 2019, 40 (5) 827-833; DOI: https://doi.org/10.3174/ajnr.A6029
J. Choi
aFrom the Department of Radiology (J.C.), St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Gyeonggi-do, Republic of Korea
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B. Kim
bDepartment of Radiology (B.K., Y.C., N.Y.S., J.J., H.S.C., S.L.J., K.J.A.), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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Y. Choi
bDepartment of Radiology (B.K., Y.C., N.Y.S., J.J., H.S.C., S.L.J., K.J.A.), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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N.Y. Shin
bDepartment of Radiology (B.K., Y.C., N.Y.S., J.J., H.S.C., S.L.J., K.J.A.), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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J. Jang
bDepartment of Radiology (B.K., Y.C., N.Y.S., J.J., H.S.C., S.L.J., K.J.A.), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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H.S. Choi
bDepartment of Radiology (B.K., Y.C., N.Y.S., J.J., H.S.C., S.L.J., K.J.A.), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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S.L. Jung
bDepartment of Radiology (B.K., Y.C., N.Y.S., J.J., H.S.C., S.L.J., K.J.A.), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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K.J. Ahn
bDepartment of Radiology (B.K., Y.C., N.Y.S., J.J., H.S.C., S.L.J., K.J.A.), Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
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  • Fig 1.
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    Fig 1.

    Image quality of angiography by 2 separate readers before (Phase 1) and after (Phase 2) the low-dose angiographic protocol.

  • Fig 2.
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    Fig 2.

    Representative examples of angiographic images before (A) and after (B) the low-dose angiographic protocol. These are cerebral angiograms of a patient who underwent diagnostic angiography to determine the cause of perimesencephalic subarachnoid hemorrhage.

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    Fig 3.
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    Fig 3.

    Boxplots of fluoroscopic time, DAP, AK, and image frames for diagnostic and therapeutic procedures before (Phase 1) and after (Phase 2) the low-dose angiographic protocol. Thick horizontal lines indicate median values, and diamonds indicate mean values.

Tables

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    Table 1:

    Mean image quality of angiography by 2 separate readers before and after the low-dose angiographic protocol

    Reader 1Reader 2
    Phase 14.94 ± 0.324.91 ± 0.33
    Phase 24.95 ± 0.324.94 ± 0.23
    • View popup
    Table 2:

    Mean and third quartile results for fluoroscopic time, DAP, AK, and image frames for diagnostic and therapeutic procedures before and after the low-dose angiographic protocol

    Fluoroscopic Time (min)DAP (Gy×cm2)AK (Gy)Image Frames
    Diagnostic
        Phase 1
            Mean13.0 ± 7.9140.8 ± 48.11.02 ± 0.42251.2 ± 72
            3rd quartile14.4160.81.18273
        Phase 2
            Mean11.9 ± 6.982.0 ± 30.00.61 ± 0.33222.6 ± 52
            3rd quartile13.894.10.69246
            P value.012<.001<.001<.001
    Therapeutic
        Phase 1
            Mean53.5 ± 34.1246.0 ± 148.33.67 ± 2.66287.6 ± 150
            3rd quartile64.5301.44.42341
        Phase 2
            Mean49.1 ± 32.2169.8 ± 111.63.31 ± 3.21260.2 ± 128
            3rd quartile60.0206.24.24334
            P value.237<.001.291.080
    • View popup
    Table 3:

    Summary of mean and third quartile data of DAP, fluoroscopic time, and number of image frames acquired during diagnostic cerebral angiography for intracranial aneurysms

    ReferenceNo. of PatientsDAP (Gy×cm2)Fluoroscopy Time (min)No. of Frames
    Mean3rd QuartileMean3rd QuartileMean3rd Quartile
    Phase 1506140.8160.813.014.4251.2273
    Phase 254082.094.111.913.8222.6246
    Hassan and Amelot1739843.159.75.67.5245314
    Chun et al6439136.6154.212.614.0251273
    D'Ercole et al18100142.11809.912.3220317
    Aroua et al199112112512.615679480
    Verdun et al2091107124
    Brambilla et al2118815819813.717.5
    • View popup
    Table 4:

    Summary of mean and third quartile data of DAP, fluoroscopic time, and number of image frames acquired during therapeutic cerebral angiography for intracranial aneurysms

    ReferenceNo. of PatientsDAP (Gy×cm2)Fluoroscopy Time (min)No. of Frames
    Mean3rd QuartileMean3rd QuartileMean3rd Quartile
    Phase 1144246.0301.453.564.5287.6341
    Phase 2173169.8206.249.160.0260.2334
    Hassan and Amelot177178.7111.925.734.8300428
    Chun et al6111226.0272.852.961.1241276
    D'Ercole et al1872382.248737.246.3558717
    Aroua et al195233544036.550760800
    Verdun et al2058335352
    Brambilla et al21356319.987.11053
    • View popup
    Table 5:

    The proportion of DAP contributed by rotational angiography before and after the low-dose protocola

    Phase 1Phase 2
    Diagnostic
        Total DAP (Gy×cm2)140.8 ± 48.182.0 ± 30.0
        Rotation DAP (Gy×cm2)26.3 ± 13.428.0 ± 13.7
        Rotations/total DAP18.7 %34.1 %
        No. of rotations1.49 ± 2.601.44 ± 0.68
    Therapeutic
        Total DAP (Gy×cm2)246.0 ± 148.3169.8 ± 111.6
        Rotation DAP (Gy×cm2)30.8 ± 17.025.6 ± 14.3
        Rotations/total DAP12.5 %15.1 %
        No. of rotations1.58 ± 0.791.33 ± 0.68
    • ↵a Data are means and percentages.

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American Journal of Neuroradiology: 40 (5)
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J. Choi, B. Kim, Y. Choi, N.Y. Shin, J. Jang, H.S. Choi, S.L. Jung, K.J. Ahn
Image Quality of Low-Dose Cerebral Angiography and Effectiveness of Clinical Implementation on Diagnostic and Neurointerventional Procedures for Intracranial Aneurysms
American Journal of Neuroradiology May 2019, 40 (5) 827-833; DOI: 10.3174/ajnr.A6029

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Image Quality of Low-Dose Cerebral Angiography and Effectiveness of Clinical Implementation on Diagnostic and Neurointerventional Procedures for Intracranial Aneurysms
J. Choi, B. Kim, Y. Choi, N.Y. Shin, J. Jang, H.S. Choi, S.L. Jung, K.J. Ahn
American Journal of Neuroradiology May 2019, 40 (5) 827-833; DOI: 10.3174/ajnr.A6029
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